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Challenges in Peptide Synthesis
Nowadays, well-known high-yielding protocols are available for the (automated) coupling of amino acids and the protection/deprotection steps. However, it is still not always straightforward to make specific high purity peptides, often because of following challenges:

  • Synthesis of long peptides (> 30 amino acids), especially highly hydrophobic
  • Synthesis on large scale
  • Influence of coupling agent and side chain on racemization
  • Purification
  • Determination of (optical) purity

Directory Contents
The web site "Peptide Synthesis" is an excellent starting point for both a researcher new to the field as an expert who is looking for a intuitively organized web site about this subject.

  • Introduction
  • Literature
    • Newsletters
    • Recent Reviews
    • Recent Books
    • Journals
  • Meetings/courses
    • Meetings
    • Courses
  • Expertise Centers
    • Companies
    • Societies