Robotarm-based Systems

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The automation of synthetic organic chemistry is not an easy task. It requires a precise control of a wide range of reaction requirements, as well as handling a vast array of reagents and solvents with different compatibilities and physical characteristics. In addition, the requirements of solid phase chemistry and solution phase chemistry are considerably different.

Key requirements of synthesis workstations are:

  • High chemical performance and throughput
  • Ease of operation and maintenance
  • Reliability
  • Cost
  • Automation and integration of
    • Reagent weighing/sampling
    • Reagent addition
    • Reaction incubation
    • Work-up
    • Isolation of products
    • On-line analysis

The directory gives an overview of robotarm-based systems for organic parallel synthesis which are currently on the market. It is a useful guide for evaluation of the variety of systems if there are plans to purchase one.


Typically, the information is presented in the following way:

Name System (including URL) Supplier (including URL)
Picture (optional)
  • Type of chemistry: e.g. solution phase, solid phase
  • Automation: e.g. (multiple) xyz arm(s), cylindrical arm
  • Reactor:
    • Arrangement: e.g. individual, well plate
    • Type: e.g. vials, flasks, tubes
    • Scale: e.g. 1, 5, 10, 25, 50 ml
    • Number: e.g. 6, 12, 24, 48, and 96 well formats
    • Material: e.g. glass, teflon
  • Reaction Conditions:
    • Temperature
      • Range: e.g. room temperature to 150°C or -78°C to 200°C
      • Heating system: e.g. conventional, microwave
      • Cooling system: e.g. circulating fluid, dry ice
      • Reflux condensors: Y/N
      • Independently controlled vessels: Y/N
    • Pressure range
    • : e.g. atmospheric, up to 50 bar
    • Inert conditions in reactors: Y/N
    • Use gaseous reactants: Y/N
    • Adding reagent/solvent while running: Y/N
    • Agitation: e.g. magnetic stirring, vortexing
  • Work-up/Analysis capabilities:
    • Parallel washing and cleavage: Y/N
    • Parallel on-line filtration: Y/N
    • Parallel evaporation: Y/N
    • Parallel liquid-liquid extraction: Y/N
    • Parallel solid phase extraction: Y/N
    • On-Line TLC: Y/N
    • On-Line LC or LC/MS: Y/N
    • Data transfer via RS-232 port: Y/N
  • Extra/special features:
  • Contact Information: