Welcome to Issue 1.5 of the "Organic Chemistry Newsletter". This newsletter focuses on industrial/academic organic and medicinal chemists and is distributed by subscription only.

A directory of custom synthesis companies (including five keywords) for the synthesis of screening compounds or research chemicals on a 1 mg - 1 kg scale.

http://www.organicworldwide.net/customsynthesis.html

A series of lectures that deal with the theory and practice of combinatorial chemistry techniques are available to download free of charge. They are presented by experienced researchers in the field who apply the techniques to their drug discovery projects within the pharmaceutical industry.

http://www.chemsoc.org/networks/ccn/iccsp_lectures.htm

An index of the chemical safety letters that have appeared in C&EN since 1993

http://pubs.acs.org/cen/safety/index.html

"Recent Advances in Catalytic Enantioselective Michael Additions" by Prof. Dr. Norbert Krause's (Synthesis, 171-196, 2001) is now the world's most cited chemistry paper. The article is available free of charge.

http://www.thieme-chemistry.com/thieme-chemistry/journals/info/news/krause.pdf

Serotonine, Acetylcholine, Isotretinoin
http://www.chemistry.org

Dettol
http://www.bris.ac.uk/Depts/Chemistry/MOTM/motm.htm http://www.chem.ox.ac.uk/mom/

Caspofungin acetate
http://www.prous.com/mom/mom.asp

There are about 50 million accessible chemical substances, 6 million available reagents, 7 million published chemical reactions, 16,000 protein crystal structures and 250,000 ready available small molecule X-ray structures. How to manage this vast amount of data and information?
Focus article of Chemical communications, 2002, issue 23 (free of charge) http://xlink.rsc.org/?DOI=b207793k

A database of combichem publications. http://www.monomerchem.com/cgi-local/2.0/db_search.cgi

Because of their potential importance as pharmaceuticals, the isoquinoline alkaloids and more generally the isoquinoline ring system have generated much interest from synthetic chemists and biochemists. General reactions and the applications of this type of heterocycle are presented.

http://www.ubichem.com/reveiw3.html

The largest electronic collections of analytical data represent 1% or less of the known chemical structures. The EUROSPEC project will establish the infrastructure necessary to make a high quality reference spectroscopic database with links to available associated chemical knowledge. Open for submission in 2003.

http://www.eurospec.org

http://chemclub.cambridgesoft.com/chemhumor/FStopten.cfm

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