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Welcome to Issue 2.10 of the "Organic Chemistry e-Newsletter".
The newsletter focuses on industrial/academic organic and medicinal chemists.

In this issue:

1. Launch of "Directory of Organic Chemistry Research"
2. Molecules of the Month (October 2003)
3. Upcoming Organic Chemistry Conferences (November 2003)
4. Molinspiration Property Calculator
5. JME Molecular Editor
6. The Mitsunobu Reaction
7. Temperatures of Cooling Baths
8. Hot papers of Chemical Communications
9. Chemical Reviews: 2002 Editor's Choice Articles
10. Retrosynthesis Programs



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1. Launch of "The Directory of Organic Chemistry Research"

"The Directory of Organic Chemistry Research" is an Internet-based database containing contact and research information of organic chemistry professors worldwide (over 550 records) in order to facilitate research collaborations. The access to this database is fee-based and subscribers to our newsletter receive a 20% discount when using coupon code DIR620 on check-out.

http://www.organicworldwide.net/directory/

2. Molecules of the Month (October 2003)

1,8-cineole: major component of camphor-scented essential oils found in eucalyptus leaves

Diphenhydramine hydrochloride: an antihistamine compound that also produces a sedative effect in many people

Ozone

Sucrose

http://www.chemistry.org

Dimethylmercury: one of the most potent neurotoxins known

http://www.bris.ac.uk/Depts/Chemistry/MOTM/motm.htm

Exenatide (synthetic exendin-4): a 39-amino acid peptide, in development for the treatment of type 2 diabetes

http://www.prous.com/mom/mom.asp

3. Upcoming Organic Chemistry Conferences (November 2003)

The First Lilly European Distinguished Lectureship
Asymmetric Hydrogenation
Prof. Ryoji Noyori, Nagoya University
November 12 th 2003, Namur, Belgium
http://www.chimie.fundp.ac.be/cos/lilly/lilly.html

4. Molinspiration Property Calculator

Free interactive calculation of molecular properties (including logP, polar surface area and other useful descriptors) and calculation of drug-likeness score for GPCR ligands, ion channel modulators and kinase inhibitors

http://www.molinspiration.com/cgi-bin/properties

5. JME Molecular Editor

The free JME Molecular Editor is a Java applet which allows easy creation and editing of organic molecules and reactions directly within web page, and creation of molecule SMILES or Molfile

http://www.molinspiration.com/jme/index.html

6. The Mitsunobu Reaction

The Mitsonobu reaction involves the treatment of alcohols (ROH) and acidic components (NuH) with dialkyl azodicarboxylates and trialkyl- or triarylphosphines to yield RNu. Lecture notes describing all aspects of this important reaction can be found at:

http://www.chem.wisc.edu/areas/organic/studsemin/jantzi/Mitsunobu_files/frame.htm

7. Temperature of Cooling Baths

A table with temperature of cooling baths based on composition (solvent and solid carbon dioxide/liquid nitrogen)

http://www.chem.ucla.edu/research/org/MERLIC_GROUP/c_links/cooling_baths.html

8. Hot papers of Chemical Communications

Papers featured in this section have been rated as "very significant" and "in the top 10%" of papers published by expert reviewers in the field. All of the featured articles are free to access for one month from the posting date.

Total synthesis of (±)-acetoxyodontoschismenol using zirconium chemistry

http://www.rsc.org/is/journals/current/chemcomm/cchotpapers.htm

9. Chemical Reviews: 2002 Editor's Choice Articles

Recoverable Catalysts for Asymmetric Organic Synthesis
Qing-Hua Fan, Yue-Ming Li, and Albert S. C. Chan
Chemical Reviews 2002, 102(10), 3385-3466.

http://pubs.acs.org/hotartcl/chreay/edchoice.html

10. Retrosynthesis Programs

Programs designed to assist the problem solving and decision making progress in organic chemistry can be very valuable in suggesting reaction schemes that may well result in a much better solution saving time in the laboratory. This directory gives an overview of the 14 retrosynthetic packages which are on the market or available for licensing.

http://www.organicworldwide.net/retrosynthesis.html



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Copyright (c) 2003 EcoSynth, Koen Van Aken Ed.