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Welcome to Issue 4.10 of the "Organic Chemistry e-Newsletter".
A newsletter for industrial/academic organic and medicinal chemists.

In this issue:

1. The 2005 Nobel Prize in Chemistry
2. Molecules of the Month (October 2005)
3. Upcoming Organic Synthesis Conferences (November 2005)
4. The IUPAC International Chemical Identifier
5. Book of the Month

Distribution: 1450

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1. The 2005 Nobel Prize in Chemistry

R. Grubbs, R. Schrock and Y. Chauvin are the joint winners of the 2005 Nobel Prize in Chemistry for the development of the metathesis method in organic synthesis. As a result of this new method, many syntheses and industrial processes, particularly in the areas of drugs and plastics, have been created or made more efficient.

The Nobel Prize in Chemistry 2005

2. Molecules of the Month (October 2005)

Atorvastatin: Is used for lowering cholesterol and it has been shown to be effective in preventing cardiovascular disease.

Cis-2-pentene: An example of an olefin used in metathesis.

Metformin hydrochloride: An insulin-sensitizing agent used to treat type 2 diabetes.

Metformin hydrochloride (vitamin B5): Plays a role in the breakdown of fats and carbohydrates for energy and is critical to the manufacture of red blood cells.

http://www.chemistry.org

Dimethylsulphide: A volatile organic sulphur compound responsible for 75% of the global sulphur cycle.

http://www.bris.ac.uk/Depts/Chemistry/MOTM/motm.htm

Rotigaptide: A stable antiarrhythmic peptide analogue, under clinical investigation for the treatment of arrhythmias.

http://www.prous.com/molecules/default.asp?ID=140

3. Upcoming Organic Synthesis Conferences (November 2005)

9th International Electronic Conference on Synthetic Organic Chemistry (ECSOC-9)
November 1-30

4. The IUPAC International Chemical Identifier

The IUPAC International Chemical Identifier is a non-proprietary identifier for chemical substances that can be used in printed and electronic data sources thus enabling easier linking of diverse data compilations.

Project web site and Unofficial InChI FAQ

5. Green Reaction Media in Organic Synthesis
Koichi Mikami(Editor), ISBN: 140513402X, Hardcover, Blackwell Publishing, 200 pages, 2005

Green, sustainable chemistry involves the designing of chemical processes with a view to reducing or even eliminating the use and production of hazardous materials. Recent endeavors have focused on limiting the use of organic solvents and replacing them with new, environmentally benign media. This book provides a broad overview of the three most commonly used green reaction media: Ionic Liquids, Fluorous Phases and Supercritical CO2.

Green Reaction Media in Organic Synthesis

























































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Copyright (c) 2005 EcoSynth, Koen Van Aken Ed.