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Welcome to Issue 5.04 of the "Organic Chemistry e-Newsletter".
A newsletter for industrial/academic organic and medicinal chemists.

In this issue:

1. Chemical Thesaurus Reaction Chemistry Database
2. Molecules of the Month (April 2006)
3. Upcoming Organic Synthesis Conferences (May 2006)
4. OSIRIS Property Explorer
5. Book of the month

Distribution: 1377

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1. Chemical Thesaurus Reaction Chemistry Database

The Chemical Thesaurus is a reaction chemistry information system which removes the artificial barriers between different subdisciplinary areas of chemistry by presenting a unified vision of inorganic and organic reaction chemistry. The database is a free, open access resource.

http://www.chemthes.com/

2. Molecules of the Month (April 2006)

Raloxifene: a selective estrogen receptor modulator used to treat osteoporosis.

Chlorophyll a: a green pigment used by plants in photosynthesis.

Coronene: a polynuclear aromatic hydrocarbon.

Lidocaine: a local anesthetic and an antiarrhythmic drug.

http://www.chemistry.org

Skatole: The smell of human excrement. At low concentrations, it has a rather nice, sweet smell.

http://www.bris.ac.uk/Depts/Chemistry/MOTM/motm.htm

Vildagliptin: FDA filed drug for once-daily oral treatment for type 2 diabetes.

http://www.prous.com/molecules/default.asp?ID=144

3. Upcoming Organic Synthesis Conferences (May 2006)

Synthetic Heterocyclic Chemistry
May 4-5, Barcelona, Espagne

Industrial Biotransformations
May 4-5, Barcelona, Espagne

MipTec – The 9th International Conference and Exhibition on Drug Discovery
May 8-11, Basel, Switzerland

7th Tetrahedron Symposium - challenges in organic chemistry
May 25-26, Kyoto, Japan

89th Canadian Chemistry Conference and Exhibition
May 27-31, Halifax, Canada

International Symposium on Chemistry, Biology and Medicine,
May 28 - June 1, Paphos, Cyprus

3rd IUPAC International Symposium on Macro- and Supramolecular Architectures and Materials (MAM-06): Practical Nano-Chemistry and Novel Approaches
May 28 - June 1, Tokyo, Japan

4. OSIRIS Property Explorer

On-line tool which allows to draw chemical structures and various drug-relevant properties are calculated on-the-fly. The prediction results are valued and color coded. A green color indicates drug-conform behaviour but properties with high risks of undesired effects (e.g. mutagenicity or poor intestinal absorption) are shown in red.

OSIRIS

5. Book of the month

Aziridines and epoxides are among the most widely used intermediates in organic synthesis, acting as precursors to complex molecules due to the strains incorporated in their skeletons.

Aziridines and Epoxides in Organic Synthesis

























































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Copyright (c) 2006 EcoSynth, Koen Van Aken Ed.